MODcol Multipacker^® Packing Station

MODcol® Spring® MultiPacker® Instruments

MODcol® Dynamic Axial Compression (DAC) Spring® Columns are the product of choice for chromatographers who require high performance, robustness, and long lasting columns. This highly versatile DAC technology is self-contained in a small and portable package, providing a highly advanced and flexible technology for preparative and semi-preparative chromatography columns. MODcol® Dynamic Axial Compression Spring® columns are the only mobile DAC columns on the market. They can be used without being mounted in the Multipacker® instrument with full DAC functionality. Spring® columns are available in 25mm, 50mm and 101mm i.d. and 2 lengths, which enable packed bed lengths from 5–300mm. Dynamic Axial Compression has been used for many years in process chromatography to provide long lasting columns with excellent performance. This technology was developed to address the loss of efficiency and peak symmetry that can result when many samples and large amounts of mobile phase are passed through columns with fixed low-density beds. Under these conditions the initial packing of the media particles in the column bed can be disturbed, resulting in the formation of a void at the column inlet or in a channelling through the packed bed. This compromises efficiency and peak symmetry. Such voids and channeling can be eliminated by using a DAC system that continually forces a piston against the media bed at the column inlet. Traditional DAC systems drive the piston with a hydraulic mechanism. The mechanical complexity of the hydraulic components can make it much more expensive than traditional columns. Until recently, use of DAC systems was limited to large permanent installations or expensive preparative systems where the column is an integrated part of the packing unit and can not be used independently after the packing process is finished. For the few alternative systems available for which the column can be separated from the packing unit, the DAC principle is lost when the column is separated from the packer and reduced to static axial compression (SAC) only.

Whether using Reproil®, Reprosphere® or any other chromatographic media the combined benefits of the MultiPacker® packing station and Spring® columns can deliver improved performance, productivity, and safety. Unlike competitive systems, the column can be removed from the MultiPacker® packing station and the DAC (Dynamic Axial Compression) mechanism remains contained within the column. This allows more flexibilit for column operation in the lab and the ability to pack multiple columns with a single MultiPacker® packing station. The hydraulic packing mechanism has nearly pulsation-free operation for gentle packing of fragil media. Since the system does not require electrical power, it is safe to use with many volatile solvents and in hazardous environments. The MultiPacker® packing station incorporates several safety features with redundant back-up to give users maximum conidence and peace of mind to perform in-house packing.